Hemiballism and chorea in a patient with parkinsonism due to a multisystem degeneration
Identifieur interne : 006015 ( Main/Exploration ); précédent : 006014; suivant : 006016Hemiballism and chorea in a patient with parkinsonism due to a multisystem degeneration
Auteurs : Steiger [Royaume-Uni] ; M. Pires [Royaume-Uni] ; F. Scaravilli [Royaume-Uni] ; N. P. Quinn [Royaume-Uni] ; C. D. Marsden [Royaume-Uni]Source :
- Movement Disorders [ 0885-3185 ] ; 1992.
English descriptors
- KwdEn :
- Aged, Antiparkinson Agents (adverse effects), Antiparkinson Agents (therapeutic use), Atrophy, Brain (pathology), Carbidopa (adverse effects), Carbidopa (therapeutic use), Central Nervous System Diseases (complications), Central Nervous System Diseases (pathology), Chorea, Chorea (chemically induced), Chorea (etiology), Chorea (pathology), Diagnosis, Differential, Drug Combinations, Female, Hemiballism, Humans, Levodopa (adverse effects), Levodopa (therapeutic use), Movement Disorders (etiology), Movement Disorders (pathology), Nerve Degeneration (physiology), Parkinson Disease (drug therapy), Parkinson Disease (etiology), Parkinson Disease (pathology), Parkinson's disease, Spinal Cord (pathology).
- MESH :
- chemical , adverse effects : Antiparkinson Agents, Carbidopa, Levodopa.
- chemical , therapeutic use : Antiparkinson Agents, Carbidopa, Levodopa.
- chemically induced : Chorea.
- complications : Central Nervous System Diseases.
- drug therapy : Parkinson Disease.
- etiology : Chorea, Movement Disorders, Parkinson Disease.
- pathology : Brain, Central Nervous System Diseases, Chorea, Movement Disorders, Parkinson Disease, Spinal Cord.
- physiology : Nerve Degeneration.
- Aged, Atrophy, Diagnosis, Differential, Drug Combinations, Female, Humans.
Abstract
Dyskinesias associated with dopaminergic treatment in idiopathic Parkinson's disease (PD) can be indistinguishable from those arising spontaneously in other conditions involving degeneration of, or damage to, the basal ganglia. However, those due to levodopa treatment of PD disappear on cessation of therapy. We report a patient with a clinical diagnosis of PD who, on levodopa treatment, developed hemiballism and chorea that were originally thought to be drug induced. However, the dyskinesias persisted despite stopping levodopa. Postmortem analysis showed a multisystem degeneration.
Url:
DOI: 10.1002/mds.870070115
Affiliations:
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Le document en format XML
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<term>Atrophy</term>
<term>Brain (pathology)</term>
<term>Carbidopa (adverse effects)</term>
<term>Carbidopa (therapeutic use)</term>
<term>Central Nervous System Diseases (complications)</term>
<term>Central Nervous System Diseases (pathology)</term>
<term>Chorea</term>
<term>Chorea (chemically induced)</term>
<term>Chorea (etiology)</term>
<term>Chorea (pathology)</term>
<term>Diagnosis, Differential</term>
<term>Drug Combinations</term>
<term>Female</term>
<term>Hemiballism</term>
<term>Humans</term>
<term>Levodopa (adverse effects)</term>
<term>Levodopa (therapeutic use)</term>
<term>Movement Disorders (etiology)</term>
<term>Movement Disorders (pathology)</term>
<term>Nerve Degeneration (physiology)</term>
<term>Parkinson Disease (drug therapy)</term>
<term>Parkinson Disease (etiology)</term>
<term>Parkinson Disease (pathology)</term>
<term>Parkinson's disease</term>
<term>Spinal Cord (pathology)</term>
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<term>Levodopa</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinson Disease</term>
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<term>Movement Disorders</term>
<term>Parkinson Disease</term>
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<front><div type="abstract" xml:lang="en">Dyskinesias associated with dopaminergic treatment in idiopathic Parkinson's disease (PD) can be indistinguishable from those arising spontaneously in other conditions involving degeneration of, or damage to, the basal ganglia. However, those due to levodopa treatment of PD disappear on cessation of therapy. We report a patient with a clinical diagnosis of PD who, on levodopa treatment, developed hemiballism and chorea that were originally thought to be drug induced. However, the dyskinesias persisted despite stopping levodopa. Postmortem analysis showed a multisystem degeneration.</div>
</front>
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